Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More
Most Useful Reviews
9
Prevents convulsions
I used to wake up with painful leg cramps, but after taking selenium, I've forgotten what those convulsions feel like. I will continue this for prevention purposes; it's truly made a difference for me.
Read More
9
Alleviates heaviness
Selenium has been a game-changer for me. It relieved pain in my legs and minor joints, as well as issues related to my kidneys and thyroid. Now, I can walk for hours without feeling heaviness in my legs, something I couldn’t do before.
Read More
7.5
Reduces muscle cramps
Life Extension Magnesium Caps are crafted with high-quality magnesium citrate, easily absorbed and tolerated. Each capsule contains 100mg of elemental magnesium. This supplement is beneficial for muscle relaxation, reducing muscle cramps, and enhancing joint mobility. Additionally, magnesium supports hormone production and cardiovascular health. The tasteless capsules are convenient and simple to swallow. Overall, this magnesium supplement offers reliable support for muscle health and well-being, combining optimal absorption with ease of use.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents convulsions
I used to wake up with painful leg cramps, but after taking selenium, I've forgotten what those convulsions feel like. I will continue this for prevention purposes; it's truly made a difference for me.
Read More
9
Alleviates heaviness
Selenium has been a game-changer for me. It relieved pain in my legs and minor joints, as well as issues related to my kidneys and thyroid. Now, I can walk for hours without feeling heaviness in my legs, something I couldn’t do before.
Read More
7.5
Reduces muscle cramps
Life Extension Magnesium Caps are crafted with high-quality magnesium citrate, easily absorbed and tolerated. Each capsule contains 100mg of elemental magnesium. This supplement is beneficial for muscle relaxation, reducing muscle cramps, and enhancing joint mobility. Additionally, magnesium supports hormone production and cardiovascular health. The tasteless capsules are convenient and simple to swallow. Overall, this magnesium supplement offers reliable support for muscle health and well-being, combining optimal absorption with ease of use.
Read More
7.5
Effective for skin
My legs were suffering from terrible cracking skin, but after taking selenium with iodine, I've completely forgotten about using cream. This combination is indeed beneficial, demonstrating effective composition and top quality. I highly recommend it.
Read More
6
Eases leg cramps
This medication is an excellent choice for managing chronic pain, featuring a potent blend of ingredients. It contains magnesium, vital for muscle function and recovery, which may reduce leg cramps. The formula also includes select minerals that support hormone balance, overall well-being, and energy production. With a package designed for long-term use, it ensures a consistent supply. Typically presented in capsule form, it has a minimal, tolerable taste and effectively targets specific pain issues while aiding overall health.
Read More
Frequently Asked Questions
9
Prevents convulsions
I used to wake up with painful leg cramps, but after taking selenium, I've forgotten what those convulsions feel like. I will continue this for prevention purposes; it's truly made a difference for me.
6
Eases leg cramps
This medication is an excellent choice for managing chronic pain, featuring a potent blend of ingredients. It contains magnesium, vital for muscle function and recovery, which may reduce leg cramps. The formula also includes select minerals that support hormone balance, overall well-being, and energy production. With a package designed for long-term use, it ensures a consistent supply. Typically presented in capsule form, it has a minimal, tolerable taste and effectively targets specific pain issues while aiding overall health.
9
Alleviates heaviness
Selenium has been a game-changer for me. It relieved pain in my legs and minor joints, as well as issues related to my kidneys and thyroid. Now, I can walk for hours without feeling heaviness in my legs, something I couldn’t do before.
7.5
Reduces muscle cramps
Life Extension Magnesium Caps are crafted with high-quality magnesium citrate, easily absorbed and tolerated. Each capsule contains 100mg of elemental magnesium. This supplement is beneficial for muscle relaxation, reducing muscle cramps, and enhancing joint mobility. Additionally, magnesium supports hormone production and cardiovascular health. The tasteless capsules are convenient and simple to swallow. Overall, this magnesium supplement offers reliable support for muscle health and well-being, combining optimal absorption with ease of use.
7.5
Effective for skin
My legs were suffering from terrible cracking skin, but after taking selenium with iodine, I've completely forgotten about using cream. This combination is indeed beneficial, demonstrating effective composition and top quality. I highly recommend it.
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
References
- Guay DR. Are there alternatives to the use of quinine to treat nocturnal leg cramps?. Consult Pharm. 2008;23:141.
- Roca AO, Jarjoura D, Blend D, Cugino A, Rutecki GW, et al. Dialysis leg cramps. Efficacy of quinine versus vitamin E. ASAIO J. 1992;38:M481.
- Ayres S, Mihan R. Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol). Calif Med. 1969;111:87.
